Fenistil: Remedy For Stings, Burns And Hives

Skin care is important all year round. However, it is especially important on sunny and hot days to protect your skin from insect bites, sunburn and allergic reactions. Fenistil is a great topical remedy for all these conditions.

Fenistil is a trademark in local gel. The active ingredient in this gel is dimethindene maleate. This component belongs to the group of antihistamines and is used to treat itching associated with allergic reactions, superficial burns and insect bites.

This article examines this medicine and how it works.

How does Fenistil work?

Fenistil is a topical gel used to relieve itching caused by irritated skin. It has local anesthetic properties that soothe itching caused by allergies, insect bites or burns.

Adults and children over one year can use Fenistil. Therefore, it is the perfect medicine to have available for any outdoor activity or vacation.

Contraindications

However, some people are allergic to dimethindene maleate or other ingredients found in the gel. Therefore, be sure to check the ingredient list and do not use it on anyone who is allergic to any of the ingredients in the gel.

Also read: 8 natural remedies for seasonal allergies

Anyone who is allergic can go into anaphylactic shock, which can be life-threatening. You should also avoid prolonged exposure to the sun on a treated area and it should not be used on any area of ​​the skin that has open sores.

Women who are pregnant or breastfeeding should consult a pharmacist or doctor before using Fenistil.

In the following, we will explain the following aspects of Fenistil in this article:

• How it works
• Pharmacokinetics
• Side effects

But before we can get into more detail on each of these points, we must first understand histamine, which is a substance found in our bodies that is directly related to this medication.

What is histamine?

The cells in the body synthesize the histamine molecule. It belongs to the group of biogenic amines. These are molecules generated by biological agents.

A biochemical reaction called decarboxylation produces them. This reaction takes place in a molecule called histidine due to the enzyme L-histidine decarboxylase.

In addition, bacteria in our gut flora and in the food we eat produce this enzyme. Therefore, they are able to synthesize histidine.

In general, histamine is involved in the local reactions of the immune system. In addition, it helps regulate normal gastric function and neuro-transmission system in the central nervous system.

Also read: Fight allergies with these 7 natural antihistamines

In essence, the functions of histamine include:

• Allergies: Histamine interferes with immediate hypersensitivity reactions and allergic reactions. Therefore, it directly affects both the humoral and the cellular immune response. In addition, it acts as the primary mediator for immediate hypersensitivity reactions.
• Neurotransmitter: Histamine can act as a neuromodulator, by modulating or regulating the response of other neurotransmitters.
• Cardiovascular regulation: This drug is a vasodilator due to its interaction between the H1 and H2 receptors, which are distributed in all arteries of resistance and in almost all vascular systems. This feature is very important to understand the effectiveness of Fenistil.

• Extravascular smooth muscle: It produces contractions of the smooth muscle.
• Gastric juice: This molecule helps promote secretion of gastric juice and triggers abundant secretion of acid in the parietal cells.

How does Fenistil work?

Dimethindene maleate, the active ingredient in Fenistil, works by interacting inversely with histamine H1 receptors. By blocking the binding of histamine to H1 receptors, the vascular hyperpermeability associated with immediate hypersensitivity reactions is reduced.

At low concentrations, it stimulates histamine-methyltransferase, which inactivates histamine. In addition, dimethindene maleate also has anesthetic properties when applied topically.

Pharmacokinetics and side effects

Fenil gel quickly penetrates the skin and releases its antihistamine properties within minutes. Then the effect reaches its maximum after 1-4 hours. After application, the absorption of dimethindene maleate is approx. 10% of the applied dose.

There may be side effects from this medicine. However, they are usually very mild and occur only in the area where the medicine was used.

That said, some side effects include:

• Dry skin.
• Burning sensation of the skin.
• Allergic dermatitis.

Have you ever heard of this topical medication? If you have any questions or concerns, ask a pharmacist or doctor.

Remember to use it with caution to avoid side effects.